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John Mayrose is a composer as well as an active performer, having performed and premiered new works for classical guitar, electric guitar, electric bass, mandolin, banjo and MIDI guitar, as well as more traditional performances on classical guitar. He holds a Ph.D. in composition at Duke University and a B.M. degree from the University of South Carolina Honors College. His teachers have included Stephen Jaffe, Scott Lindroth, Sidney Hodkinson, Anthony Kelley, Christopher Berg, and Michael Cedric Smith.

John's music has been played throughout North America, Europe, and Australia, by among others, Duo 46, Amphion Percussion, Michael Mizrahi, Fireworks, pulsoptional, Jillon Stoppels Dupree, Duo d'amore, the University of North Carolina Wind Symphony, and percussion ensembles at Truman State University, the University of Texas, Central Michigan University, and Lawrence University. He is the recipient of the first place prize in the Percussive Arts Society Composition Contest (2009), the ASCAP Plus Award, the Aliénor Harpsichord Composition Prize (2008), the William Klenz Prize in Composition (2001), the ASCAP Morton Gould Young Composer's Award (2004) for "What Hath God Wrought": Reflections on a Theme by Samuel F. B. Morse, the Bass Named Instructorship (Duke 2005/2006), the Mary Duke Biddle Fellowship, and several University of Wisconsin Oshkosh Faculty Development Grants. John is a member of the new music ensemble pulsoptional, a composer's collective based in Durham, North Carolina. His music has been featured in the Electronic Music Midwest Festival, Western Illinois New Music Festival, the Aspen Music Festival, Oregon Bach Festival, the Boston Early Music Festival, and North Carolina HIP Festival.

John is an Assistant Professor of Music at the University of Wisconsin Oshkosh. He has taught at Indiana University South Bend and served as the Postdoctoral Fellow in Music Composition at the Lawrence University Conservatory of Music where he was also the director of the Improvisation Group of Lawrence University.